{"id":18175,"date":"2020-06-20T19:46:55","date_gmt":"2020-06-20T19:46:55","guid":{"rendered":"http:\/\/www.africanchallenges.com\/?p=18175"},"modified":"2020-06-20T19:50:50","modified_gmt":"2020-06-20T19:50:50","slug":"covid-19-loms-se-rejouit-des-resultats-preliminaires-de-lutilisation-de-la-dexamethasone","status":"publish","type":"post","link":"https:\/\/www.africanchallenges.com\/?p=18175","title":{"rendered":"Covid-19 : L\u2019OMS se r\u00e9jouit des r\u00e9sultats pr\u00e9liminaires de l\u2019utilisation de la dexam\u00e9thasone"},"content":{"rendered":"\n<p><strong>L\u2019Organisation mondiale de la Sant\u00e9 (OMS) se r\u00e9jouit des premiers r\u00e9sultats d\u2019essais cliniques men\u00e9s au Royaume-Uni qui montrent que la dexam\u00e9thasone, un corticost\u00e9ro\u00efde, pourrait sauver la vie de patients gravement malades de la COVID-19. D\u2019apr\u00e8s ces donn\u00e9es pr\u00e9sent\u00e9es \u00e0 l\u2019OMS, le traitement a d\u00e9montr\u00e9 sa capacit\u00e9 \u00e0 r\u00e9duire la mortalit\u00e9 d\u2019un tiers environ pour les patients sous respirateur, tandis que pour les patients ayant seulement besoin d\u2019oxyg\u00e8ne, la mortalit\u00e9 a \u00e9t\u00e9 r\u00e9duite d\u2019un cinqui\u00e8me environ.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n<p>Ce b\u00e9n\u00e9fice a \u00e9t\u00e9 observ\u00e9 uniquement chez les patients gravement maladies de la COVID-19, et non chez ceux pr\u00e9sentant des formes plus b\u00e9nignes.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n<p>\u00ab\u00a0C\u2019est la premi\u00e8re fois qu\u2019un traitement d\u00e9montre sa capacit\u00e9 \u00e0 r\u00e9duire la mortalit\u00e9 chez les patients COVID-19 ayant besoin d\u2019oxyg\u00e8ne ou d\u2019une ventilation m\u00e9canique\u00a0\u00bb a d\u00e9clar\u00e9 le D<sup>r<\/sup>\u00a0Tedros Adhanom Ghebreyesus, Directeur g\u00e9n\u00e9ral de l\u2019OMS. \u00ab\u00a0C\u2019est une nouvelle formidable et je tiens \u00e0 remercier le Gouvernement du Royaume-Uni, l\u2019Universit\u00e9 d\u2019Oxford et les nombreux h\u00f4pitaux et patients du Royaume-Uni qui ont contribu\u00e9 \u00e0 cette avanc\u00e9e scientifique d\u2019importance vitale.\u00a0\u00bb\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n<p>La dexam\u00e9thasone est un st\u00e9ro\u00efde employ\u00e9 depuis les ann\u00e9es 60 pour r\u00e9duire l\u2019inflammation pour toute une gamme d\u2019affections, y compris des troubles inflammatoires et certains cancers. Ce m\u00e9dicament figure depuis 1977 sur la Liste mod\u00e8le OMS des m\u00e9dicaments essentiels, sous de multiples formulations. D\u00e9sormais dans le domaine public, il est disponible \u00e0 un prix abordable dans la plupart des pays.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n<p>Les chercheurs ont communiqu\u00e9 \u00e0 l\u2019OMS de premiers \u00e9l\u00e9ments sur les r\u00e9sultats de l\u2019essai et nous attendons avec int\u00e9r\u00eat l\u2019analyse compl\u00e8te des donn\u00e9es qui devrait nous \u00eatre adress\u00e9e dans les prochains jours. L\u2019OMS coordonnera une m\u00e9ta-analyse pour am\u00e9liorer sa compr\u00e9hension globale de l\u2019intervention. Les orientations cliniques de l\u2019OMS seront actualis\u00e9es afin d\u2019indiquer quand et comment le m\u00e9dicament doit \u00eatre utilis\u00e9 contre la COVID-19.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n<p>L\u2019annonce faite aujourd\u2019hui trouve son origine dans la r\u00e9union sur le sch\u00e9ma directeur de l\u2019OMS pour la recherche-d\u00e9veloppement, tenue \u00e0 Gen\u00e8ve mi-f\u00e9vrier pour acc\u00e9l\u00e9rer le d\u00e9veloppement des technologies sanitaires contre la COVID-19, lors de laquelle les recherches compl\u00e9mentaires sur l\u2019utilisation des st\u00e9ro\u00efdes ont \u00e9t\u00e9 d\u00e9finies comme un axe prioritaire. Ces r\u00e9sultats soulignent une nouvelle fois l\u2019importance d\u2019essais contr\u00f4l\u00e9s randomis\u00e9s capables de produire des donn\u00e9es exploitables. L\u2019OMS continuera de collaborer avec l\u2019ensemble des partenaires pour mettre au point des traitements et des vaccins salvateurs contre la COVID-19, notamment sous l\u2019\u00e9gide du Dispositif d\u2019acc\u00e9l\u00e9ration de l\u2019acc\u00e8s aux outils de lutte contre la COVID-19.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"L\u2019Organisation mondiale de la Sant\u00e9 (OMS) se r\u00e9jouit des premiers r\u00e9sultats d\u2019essais cliniques men\u00e9s au Royaume-Uni qui montrent que la dexam\u00e9thasone, un corticost\u00e9ro\u00efde, pourrait sauver la vie de patients gravement malades de la COVID-19. D\u2019apr\u00e8s ces donn\u00e9es pr\u00e9sent\u00e9es \u00e0 l\u2019OMS, le traitement a d\u00e9montr\u00e9 sa capacit\u00e9 \u00e0 r\u00e9duire la mortalit\u00e9 d\u2019un tiers environ pour les [...]","protected":false},"author":4,"featured_media":14900,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","jnews-multi-image_gallery":[],"jnews_single_post":{"subtitle":"","format":"standard","video":"","gallery":"","source_name":"","source_url":"","via_name":"","via_url":"","override":[{"single_blog_custom":"","sidebar":"","second_sidebar":"","share_position":"","share_float_style":"","post_date_format":"","post_date_format_custom":"","post_reading_time_wpm":"","zoom_button_out_step":"1","zoom_button_in_step":"1","number_popup_post":"1"}],"image_override":[{"single_post_thumbnail_size":"","single_post_gallery_size":""}],"trending_post_position":"","trending_post_label":""},"jnews_primary_category":{"id":""},"jnews_override_bookmark_settings":[],"jnews_review":[],"enable_review":"","type":"","name":"","summary":"","brand":"","sku":"","good":[],"bad":[],"score_override":"","override_value":"","rating":[],"price":[],"jnews_post_split":[],"footnotes":""},"categories":[11],"tags":[4644,4641,4642,4643],"class_list":["post-18175","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-dexamethasone","tag-loms","tag-rejouit","tag-utilisation"],"_links":{"self":[{"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/posts\/18175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18175"}],"version-history":[{"count":2,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/posts\/18175\/revisions"}],"predecessor-version":[{"id":18178,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/posts\/18175\/revisions\/18178"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=\/wp\/v2\/media\/14900"}],"wp:attachment":[{"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18175"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18175"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.africanchallenges.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}